The unpredictability inherent in human affairs is due largely to the fact that the by-products of a human process are more fateful than the product.
— Eric Hoffer

Superstition, bigotry and prejudice, ghosts though they are, cling tenaciously to life; they are shades armed with tooth and claw. They must be grappled with unceasingly, for it is a fateful part of human destiny that it is condemned to wage perpetual war against ghosts. A shade is not easily taken by the throat and destroyed.
Victor Hugo fateful quote

When a decision is made to go to war based on intelligence, it is a fateful decision. It has ramifications and impacts way beyond the current months and years.
— Carl Levin

That fateful stretch of road has since been dubbed the Highway of Death.
— John Whitehead

We all have such fateful objects -- it may be a recurrent landscape in one case, a number in another -- carefully chosen by the gods to attract events of specific significance for us: here shall John always stumble; there shall Jane's heart always break.
— Vladimir Nabokov